Supports digestive health when consumed daily:

• Kalman DS, Schwartz HI, Alvarez P, Feldman S, Pezzullo JC, Krieger DR.
  A Prospective, Randomized, Double-blind, Placebo-controlled Parallel-group Dual Site Trial to Evaluate the Effects of a Bacillus coagulans–based Product on Functional Intestinal Gas Symptoms BMC gastroenterology 2009. 9:85.
• Hun L. Bacillus coagulans Significantly Improved Abdominal Pain and Bloating in Patients With IBS Postgrad Med 2009.121:119-24.
  Dolin BJ. Effects of A Proprietary Bacillus coagulans Preparation on Symptoms of Diarrhea–Predominant Irritable Bowel Syndrome Methods Find Exp Clin Pharmacol 2009. 31:655-9.

IMMUNE HEALTH

Daily consumption helps create a healthier intestinal environment, supporting immune function:

• Anaya-Loyola MA, Enciso-Moreno JA, Lopez-Ramos JE, Garcia-Marin G, Orozco Alvarez MY, Vega-Garcai AM, Mosqueda J, Garcia-Gutierrez DG, Keller D, Perez-Ramirez IF. Bacillus coagulans GBI-30, 6086 decreases upper respiratory and gastrointestinal tract symptoms in healthy Mexican scholar-aged children by modulating immune-related proteins. (2019)
• Kimmel M, Keller D, Farmer S, Warrino DE. A Controlled Clinical Trial to Evaluate the Effect of GanedenBC30 on Immunological Markers Methods Find Exp Clin Pharmacol 2010;32:129-32.

PROTEIN UTILIZATION

May help with protein utilization and muscle recovery:

• Keller D, Van Dinter R, Cash H, Farmer S, Venema K Bacillus coagulans GBI-30, 6086 increases plant protein digestion in a dynamic, computer-controlled in vitro model of the small intestine Benef Microbes 2017:1-6
• Jäger R, Shields KA, Lowery RP, et al. Probiotic Bacillus coagulans GBI-30, 6086 reduces exercise-induced muscle damage and increases recovery PeerJ 2016;4:e2276
• Maathuis AJ, Keller D, Farmer S, Gepner Y, Hoffman JR, Shemesh E, et al. Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine. Benef Microbes 2010;1:31-6.
• Gepner Y, Hoffman JR, Shemesh E, et al. The Combined Effect of Bacillus Coagulans GBI-30, 6086 and HMB Supplementation on Muscle Integrity and Cytokine Response during Intense Military Training. J Appl Physiol 2017:jap 01116 2016.

C8Vantage

C8 MCT for increasing ketogenicity, satiety and energy intake, increase fat oxidation and enhance exercise endurance:

• Papamandjaris AA, et al. Medium chain fatty acid metabolism and energy expenditure: obesity treatment implications. Life Sci. 1998. 62: 1203–1215.
• Wang Y, et al. Medium Chain Triglycerides enhances exercise endurance through the increased mitochondrial biogenesis and metabolism. PLOS. 2018.
• Vandenberghe C, St Pierre V, Pierotti T. Tricaprylin alone increase plasma ketone response more than coconut oil or other medium-chain triglycerides: an acute crossover study in healthy adults. Curr Dev Nutr. 2017. 1(4): e000257.
• Maher T, et al. Food intake and satiety response after medium-chain triglycerides ingested as solid or liquid. Nutrients. 2019. 11(7): 1638.
• Khabbush A, Orford M, Tsai YC, et al. Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium chain triglyceride ketogenic diet. Epilepsia. 2017. 58(8): 1423.
• Nosaka N, et al. Effect of ingestion of medium chain triacylglycerols on moderate and high intensity exercise in recreational athletes. J Nutr Sci Vitaminol. 2009. 55(2): 120-5.